Bio- ja ympäristötieteiden laitos

Spectroscopy on biomolecules

Research topic: Spectroscopy on biomolecules

 

The group of Prof. Janne Ihalainen (JYU/NSC) started at the division of Cell and Molecular Biology in January 2009. The research interests of the group lay at the intersection of biology, chemistry and physics and it develops (micro)spectroscopic tools for characterization of biomolecules. The experimental approaches used in the studies are for example time-resolved fluorescence, transient absorption (VIS–VIS and VIS–MIR), and Raman techniques.

 

 

Selected publications:


Janne A. Ihalainen, Beatrice Paoli, Stefanie Muff, Ellen H.G. Backus,

Jens Bredenbeck, G. Andrew Woolley, Amedeo Caflisch, Peter Hamm: a-helix

folding in the presence of structural constraints. Proc. Natl. Acad.

Sci. 2008, 105, 9588-9593.


Janne A. Ihalainen, Jens Bredenbeck, Rolf Pfister, Jan Helbing, Lei

Chi, Ivo H.M. van Stokkum G. Andrew Woolley, Peter Hamm: Folding and

unfolding of a photoswitchable peptide from picoseconds to microseconds.

Proc. Natl. Acad. Sci. 2007, 104, 5383-5388.


C.D. van der Weij – de Wit, J.A. Ihalainen, R. van Grondelle, J.P.

Dekker: Excitation Energy Transfer in Native and Unstacked Thylakoid

Membranes Studied by Low Temperature and Ultrafast Fluorescence

Spectroscopy. Photosynth. Res. 2007. 93, 173 - 182.


Janne A. Ihalainen, Roberta Croce, Tomas Morosinotto, Ivo H.M. van

Stokkum, Roberto Bassi, Jan P. Dekker, Rienk van Grondelle: Excitation

decay pathways of Lhca proteins - A time-resolved fluorescence study. J.

Phys. Chem. B 2005, 109, 21150-21158.


Janne A. Ihalainen, Sandrine D'Haene, Nataliya Yeremenko, Henny van

Roon, Ana A. Arteni, Egbert J. Boekema, Rienk van Grondelle, Hans C.P.

Matthijs, Jan P. Dekker: Aggregates of the chlorophyll-binding protein

IsiA (CP43') dissipate energy in cyanobacteria. Biochemistry 2005, 44,

10846-10853.