26.09.2016

Agilent 6460 LC/MS-MS

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Agilent 6460 Liquid Chromatograph (LC) with Mass Selective detector (MS)

Agilent6460.jpg

Agilent 6460 mass spectrometer/liquid chromatograph system. (Picture taken by Saku Mattila.)

Name and Model (Year of Manufacture / Installation)

Agilent Technologies 6460 LC/MS-MS (2010/2010)

General Information        

Liquid Chromatography/Mass selective detector (LC/MS/MS) Triple Quadrupole system. The equipment is used for structural characterization and accurate mass determinations from organic compounds.  

Suomeksi: Lähinnä orgaanisten yhdisteiden kvalitatiiviseen, kvantitatiiviseen ja rakenneanalytiikkaan tarkoitettu nestekromatografimassaspektrometri.

Key Specifications    
  • LC/MS-MS system
  • m/z range: 5 to 3000 m/z
  • Polarity switching: 30 ms
  • Mass resolution:
    • Autotune, full width at half maximum 0.7 Da
    • Manual tune, full width at half maximum 0.5 Da
    • Mass accuracy:
      • 0.1 Da from 5 to 1000 m/z
      • 0,01 % from 1000 to 2000 m/z
      • 0,02 % from 2000 to 3000 m/z
      • Mass stability: <0.1 Da in 24 h
      • Dynamic range: 6.0 x 106
      • Maximum scan rate: 12500 Da/s
      • Minimum MRM dwell time: 1 ms
      • MRM transitions: 450 per time segment, >13500 ion transitions per method
      • Dynamic MRM transitions: 4500 ion transitions per method
      • Triggered MRM transitions: Up to 10 MRM transitions (primary and secondary) for library search and compound confirmation
      • Collision cell ion clearance: < 1 ms

 

General specifications

Solvent declustering: Countercurrent gas

Detector: High-energy conversion dynode and high-gain electron multiplier horn.

Autotune: Automated optimization of ion optics and mass axis calibration in positive and negative ion modes using a proprietary tune solution.

Key Features   

  • Ion source: Electrospray ionization (ESI)
  • Mode: Positive or Negative Ion capability
Location, Contact Person

Department of Chemistry, YSK 341 / Jukka Pekka Isoaho