High level research at the nanoscale

The Nanoscience Center hosts more than hundred researchers with a background in biology, chemistry or physics. The strength of Nanoscience Center is that there are people from all areas, from practical biologists to theoretical physicists. In addition to experimental work, substantial effort is invested in the theoretical and computational study of nanosystems.

From symmetry breaking to unraveling the origin of the chirality of ligated Au13Cu2 nanoclusters

This collaborative work between NSC (Acad. prof. Häkkinen) and Xiamen University (prof. Nanfeng Zheng) demonstrates a new method to synthesize and characterize optically pure ultra-small chiral Au-Cu clusters protected by pyridinethiols and chiral diphosphines. DFT calculations done at the NSC reveal the details of the origin of the chiral optical response of these nanomaterials, which resist racemization up to 70 C making them potentially interesting materials for enantioselective catalysis.

G. Deng, S. Malola, J. Yan, J. Han, P. Yuan, C. Zhao, X. Yuan, S. Lin, Z. Tang, B. K. Teo, H. Häkkinen, N. Zheng, Angewandte Chemie.

Extinct type of human parvovirus B19 persists in tonsillar B cells


Research groups from the Nanoscience Center in the University of Jyväskylä and Department of Virology in the University of Helsinki have reported that Parvovirus B19 (B19V) DNA persists lifelong in human tonsillar tissues. The B19V DNA is most frequent and abundant among B cells, and within them they find a B19V genotype that vanished from circulation 440 years ago. The research was published in Nature Communications.

Pyöriä Lari, Toppinen Mari, Mäntylä Elina, Hedman, Aaltonen Leena-Maija, Vihinen-Ranta Maija, Ilmarinen Taru, Söderlund-Venermo Maria, Hedman Klaus, Perdomo Maria. Nature Communications Nature Communications 4;8: 14930. https://www.nature.com/articles/ncomms14930 and nature microbiology community http://go.nature.com/2o38v0S

Building miniature optical antennas using DNA as a guide 21519df3-de61-4dfb-9263-402c8bf591a0-2.jpeg

Research groups from University of Jyväskylä and Aalto University (Finland) together with researchers from California Institute of Technology (Caltech, USA) and Aarhus University (iNANO Center, Denmark) have reported a new highly parallel technique to fabricate precise metallic nanostructures with designed plasmonic properties by means of different self-assembled DNA origami shapes. The so-called DALI (DNA-assisted lithography) method has been published in the latest issue of Science Advances.

Boxuan ShenVeikko LinkoKosti TapioSiim Pikker, Tibebe LemmaAshwin GopinathKurt V. GothelfMauri A. Kostiainen and J. Jussi Toppari, Plasmonic nanostructures through DNA-assisted lithographyScience Advances, 4, 8978 (February 2, 2018) http://dx.doi.org/10.1126/sciadv.aap8978

New research opening for atomically thin metal nanostructures45b64cc2-1239-4ea2-81b9-337b0ca5bc47.png

Researchers at the Nanoscience Center in the University of Jyväskylä predict systematically the properties of atomically thin structures made exclusively from metallic elements. This provides an atlas for two-dimensional elemental metals.

Janne Nevalaita, Pekka Koskinen, An Atlas of two-dimensional elemental metals, https://journals.aps.org/prb/abstract/10.1103/PhysRevB.97.035411

Helium ions reveal how viruses attack bacteria bakteriofaagit.jpg

An interdisciplinary research consortium from the Nanoscience Center at University of Jyvaskyla in Finland (group leaders Dr. Lotta-Riina Sundberg and Prof. Ilari Maasilta) has found that bacteria and viruses can be imaged with helium ions in contrast to electrons which are the standard workhorse in nanoscale microscopy. Helium ions, being more massive than electrons, can be focused to a much tighter spot down to the atomic length scales. By measuring the electrons generated by the ion bombardment, an image can be formed from the sample with biological features visible below the nanometer (one billionth of a meter) length.

M. Leppänen, L.-R. Sundberg, E. Laanto, G. Magno de Freitas Almeida, P. Papponen and I. J. Maasilta, "Imaging Bacterial Colonies and Phage–Bacterium Interaction at Sub-Nanometer Resolution Using Helium-Ion Microscopy", Advanced Biosystems 1, 1700070 (2017)


Quantum theory for manipulating nanomagnets 

Researchers at the Department of Physics, Universityof Jyväskylä, Finland, have created a theory that predicts the properties of nanomagnets manipulated with electric currents. This theory is useful for future quantum technologies. The research was published in Physical Review Letters.

P. Virtanen and T.T. Heikkilä, ”Spin Pumping and Torque Statistics in the Quantum Noise Limit”, Physical Review Letters 118, 237701 (2017)

Researchers beat the quantum limit of microwave measurements rumpuwiggle.jpg

Research groups at Aalto University and the University of Jyväskylä have demonstrated a new microwav measurement method that goes to the quantum limit of measurement and beats it. The new method can potentially be used for example in quantum computing and measurement of gravitational waves.

C. F. Ockeloen-Korppi, E. Damskägg, J.-M. Pirkkalainen, T. T. Heikkilä, F. Massel, and M. A. Sillanpää: "Noiseless Quantum Measurement and Squeezing of Microwave Fields Utilizing Mechanical Vibrations”, Physical Review Letters 118, 103601 (2017)