Host-pathogen interactions - virus infection mechanisms and antiviral development

Sisällysluettelo

Tutkimusryhmän tyyppi
Research group
Tutkimuksen painoala
Basic natural phenomena and mathematical thinking
Tutkimusalueet
Nanobiology
Nanoscience Center
Health and well-being (NSC)
Tiedekunta
Faculty of Mathematics and Science
Osasto
Department of Biological and Environmental Science

Tutkimusryhmän kuvaus

The research interest of Marjomäki group is to elucidate the host factors that affect virus stability, or promote viral uncoating and genome release from endosomes. Marjomäki group has a long-established experience on studying the cell biology of human enteroviruses. Recent major focus in the laboratory is to study the mechanistic basis of potential antiviral molecules that have recently been found for enteroviruses and coronaviruses from several molecular and drug screens.

Julkaisut

Julkaisu
2018

A novel rat CVB1-VP1 monoclonal antibody 3A6 detects a broad range of enteroviruses

Scientific Reports.
Saarinen, Niila V. V.
Laiho, Jutta E.
Richardson, Sarah J.
Zeissler, Marie
Stone, Virginia M.
Marjomäki, Varpu
Kantoluoto, Tino
Horwitz, Marc S.
Sioofy-Khojine, Amirbabak
Honkimaa, Anni
Hankaniemi, Minna M.
Flodström-Tullberg, Malin
Hyöty, Heikki
Hytönen, Vesa P.
Laitinen, Olli H.
Julkaisu
2018

Novel activities of safe-in-human broad-spectrum antiviral agents

Antiviral Research.
Ianevski, Aleksandr
Zusinaite, Eva
Kuivanen, Suvi
Strand, Mårten
Lysvand, Hilde
Teppor, Mona
Kakkola, Laura
Paavilainen, Henrik
Laajala, Mira
Kallio-Kokko, Hannimari
Valkonen, Miia
Kantele, Anu
Telling, Kaidi
Lutsar, Irja
Letjuka, Pille
Metelitsa, Natalja
Oksenych, Valentyn
Bjørås, Magnar
Nordbø, Svein Arne
Dumpis, Uga
Vitkauskiene, Astra
Öhrmalm, Christina
Bondeson, Kåre
Bergqvist, Anders
Aittokallio, Tero
Cox, Rebecca J.
Evander, Magnus
Hukkanen, Veijo
Marjomäki, Varpu
Julkunen, Ilkka
Vapalahti, Olli
Tenson, Tanel
Merits, Andres
Kainov, Denis
Julkaisu
2017

Antiviral Properties of Chemical Inhibitors of Cellular Anti-Apoptotic Bcl-2 Proteins

Viruses.
Bulanova, Daria
Ianevski, Aleksandr
Bugai, Andrii
Akimov, Yevhen
Kuivanen, Suvi
Paavilainen, Henrik
Kakkola, Laura
Nandania, Jatin
Turunen, Laura
Ohman, Tiina
Ala-Hongisto, Hanna
Pesonen, Hanna M.
Kuisma, Marika S.
Honkimaa, Anni
Walton, Emma L.
Oksenych, Valentyn
Lorey, Martina B.
Guschin, Dmitry
Shim, Jungmin
Kim, Jinhee
Than, Thoa T.
Chang, So Young
Hukkanen, Veijo
Kulesskiy, Evgeny
Marjomäki, Varpu
Julkunen, Ilkka
Nyman, Tuula A.
Matikainen, Sampsa
Saarela, Jani S.
Sane, Famara
Hober, Didier
Gabriel, Gülsah
De Brabander, Jef K.
Martikainen, Miika
Windisch, Marc P.
Min, Ji-Young
Bruzzone, Roberto
Aittokallio, Tero
Vähä-Koskela, Markus
Vapalahti, Olli
Pulk, Arto
Velagapudi, Vidya
Kainov, Denis E.
Julkaisu
2017

Regulation of Kynurenine Biosynthesis during Influenza Virus Infection

FEBS Journal.
Gaelings, Lana
Söderholm, Sandra
Bugai, Andrii
Fu, Yu
Nandania, Jatin
Schepens, Bert
Lorey, Martina B.
Tynell, Janne
Ginste, Liesbeth Vande
Goffic, Ronan Le
Miller, Matthew S.
Kuisma, Marika
Marjomäki, Varpu
De Brabander, Jef
Matikainen, Sampsa
Nyman, Tuula A.
Bamford, Dennis
Saelens, Xavier
Julkunen, Ilkka
Paavilainen, Henrik
Hukkanen, Veijo
Velagapudi, Vidya
Kainov, Denis E.

Tutkimusryhmä

Tutkimusryhmän vetäjät

Varpu Marjomäki

Varpu Marjomäki

Professor, Vice Head of Department

Jäsenet

Mira Laajala

Postdoctoral Researcher

Kati Karvonen

Coordinator

Marjo Haapakoski

Doctoral Researcher

Jun Liu

Doctoral Researcher

Laura Myllymäki

Doctoral Researcher