Efficient plant-based production of proteins and vaccines
Omayra Bolaños-Martínez , PhD
The biopharmaceuticals industry demands new production platforms to address several challenges: production cost reduction, safety enhancement, and development of products administered by noninvasive routes. Plants are innovative hosts with the potential to meet such requirements. Successful cases of producing antibodies, antimicrobial peptides, growth factors, hormones, and vaccines in plants have been reported. The transient plant-based expression approach using the Agro-infiltration method will be addressed, as well as the production of viral capsid proteins and glyco enzymes. The collaboration project “Production of Coxsackie B virus-like particles in tobacco plants” between the Department of Applied Genetic and Cell Biology (DAGZ), BOKU, Vienna, Austria, and the Department of Biological and Environmental Science, JYU, Jyväskylä, Finland is presented.
