Leveraging state dependent viscera-brain coupling to identify novel treatment targets for mental health disorders

Table of contents

Project duration
-
Core fields of research
Physical activity, health and wellbeing
Research areas
CIBR - Research areas
Department
Department of Psychology
Faculty
Faculty of Education and Psychology
Funding
Research Council of Finland

Project description

The brain continuously senses signals from within the body and the rhythms of the heart, lungs, and stomach have a large impact on brain signals and cognition. To which extent is the coupling between the brain and viscera dependent on different states (e.g. being active versus resting) and is it possible to change the strength of this connection? This is especially relevant given that how connected the brain is to these signals might directly impact our mental health. This project will further our fundamental understanding on the nature of this brain-body coupling, test a new paradigm to change the strength of the coupling, and quantify whether psychopathological symptoms are driven by changes in viscera-brain coupling. The project, conducted at the university of Jyväskylä, will use a combination of state-of-the-art neuroimaging, brain stimulation and computational modeling. The findings of the experiments will open new possibilities for treating mental ill-health.

Project team

External members

Sanne ten Oever

Maastricht University

Sara Määttä

Kuopio University Hospital

Marion Rouault

Paris Brain Institute

Anke Karabanov

Copenhagen University